The Science
The Science Behind Methylene Blue
A molecule with a history — and a future.
Originally developed in the 19th century as a textile dye, methylene blue has since been studied extensively for its applications in cellular and mitochondrial health. Its powerful redox properties make it a compound of growing interest across neuroscience, longevity research, and cellular energy studies.
How It Works: Mitochondrial Support
Methylene blue acts as an electron cycler, meaning it can shuttle electrons within the mitochondria — your body’s energy powerhouses. This helps improve the efficiency of ATP production, especially under oxidative stress.
- Supports mitochondrial respiration
- Reduces reactive oxygen species (ROS)
- Promotes cellular resilience
In essence, methylene blue may help your cells make energy more efficiently while protecting against cellular stress.
Cognitive Function & Neuroprotection
Peer-reviewed studies have suggested that low doses of methylene blue may enhance memory consolidation, working memory, and cerebral oxygenation.
- It has been explored as a nootropic compound due to its impact on:
- Mitochondrial energy in brain cells
- Potential protective effects against neurodegeneration
- Mental clarity and processing speed
Dosage in Research Contexts
While our product is for research purposes only, here are references from peer-reviewed literature:
- ~0.5 mg/kg is a common dosage explored in cognitive and mitochondrial studies
- 10 drops of a 2% solution = approx. 10 mg of methylene blue
- Research-grade applications have used doses ranging from 0.25–4 mg/kg
Safety & Considerations
Contraindications:
Methylene blue should not be used in combination with SSRIs, MAOIs, or SNRIs, and is contraindicated in individuals with G6PD deficiency.
Disclaimer:
This product is not intended to diagnose, treat, cure, or prevent any disease. For laboratory, research, or external use only. Not for therapeutic use. Always consult a medical professional before handling.
Further Reading
Want to explore more? Here are a few foundational studies and reviews: